CD BioGlyco, a biotechnology company that provides a full range of glycobiology-related products, analysis, and custom synthesis to the science community, now provides custom glycosylation of antibodies service for research use.

 

Antibodies are important components of many diseases’ protective immune responses, acting as cell-associated and soluble receptors for foreign substances. Variable domains (F(ab’)₂) and constant domains (Fc) make up antibodies. F(ab’)₂ is in charge of antigen recognition, and the Fc region interacts with various Fc receptors and complement proteins. Antibody glycosylation is a common post-translational modification that is essential for antibody function. The rapid expansion of therapeutic antibody repertoires has fueled interest in antibody glycosylation in recent years. Antibodies with specific glycoforms are produced by glycoengineering to achieve the desired therapeutic effect.

 

Now, skilled and experienced scientists at CD BioGlyco are able to perform custom glycosylation service of antibodies based on customers’ specific needs and guide them through the whole process.

 

Services at CD BioGlyco now include:

Modification of antibody glycosylation

CD BioGlyco has various glycosylation technologies and offers a variety of antibody glycosylation services, such as fucose deficiency, sialylation, and so on.

 

Characterization of antibody glycosylation

CD BioGlyco performs antibody glycosylation analysis using a variety of techniques, including capillary electrophoresis (CE), high-performance liquid chromatography (HPLC), electrospray ionization mass spectrometry (ESI-MS), Fourier ion cyclotron resonance mass spectrometry (FT-ICR-MS), size exclusion chromatography (SEC), and matrix-assisted laser desorption ionization-time of flight mass (MALDI-TOF MS).

 

“We are dedicated to providing provides high-quality, cost-effective, and hassle-free custom glycosylation of antibodies. Hope we can become your indispensable assistant in the glycosylation field.” Said Anna, one of the representative speakers from CD BioGlyco.

 

In addition, CD BioGlyco provides custom glycosylation of proteins, cell membranes and bacterial membranes to assist scientists with their research.

 

More information about the custom glycosylation of antibodies provided by CD BioGlyco, please visit https://www.bioglyco.com/custom-glycosylation-of-antibodies.html.